Georges was married three times: to Jeanne Schnyder in 1932, Monique Panchaud de Bottens in 1949, and Helen Mary Dale.On his father's death in 1966, de Mestral inherited the family home at Colombier, château Saint-Saphorin-sur-Morges.
De Mestral died in Commugny, Switzerland, where he is buried. The municipality posthumously named an avenue, L'avenue Georges de Mestral, in his honor.[1] He was inducted into the National Inventors Hall of Fame in 1999 for inventing Velcro hook and loop fasteners.