Centella asiatica and Punica granatum are medicinal plants that have
been reported to promote tissue healing and modulate host responses. Preliminary
study revealed positive clinical effects of an innovative preparation from the two
herbal extracts in the form of biodegradable chips as a subgingival adjunct to
scaling and root planing. The purpose of this research was to evaluate further
augmenting efficacy the combined herbal preparation may have among maintenance
patients in comparison to standard supportive periodontal therapy (SPT), with
additional monitoring of certain inflammatory markers.