a b s t r a c t
The continuous countercurrent fractionation of fish oil ethyl esters using supercritical carbon dioxide
is studied, modelling a process with internal reflux generated by a thermal gradient at the top stage.
A methodology for process design is proposed and applied to determine the relationships between the
temperature at the top stage (T1), the number of theoretical stages (N), and the solvent to feed ratio
(S/F), with the aim of providing a quantitative comparison with the external reflux process. The internal
reflux process is viable and, for stated process specifications (mass fraction and recovery of C20 + C22
ethyl esters of 95%), provides comparable or better results than the external reflux process. For example,
operating at 13.3 MPa and 50 ◦C, and keeping T1 in the range (66–70) ◦C, the specifications are attained
with N and S/F in the range 16–30 and 88–120, respectively.
©
a b s t r a c tThe continuous countercurrent fractionation of fish oil ethyl esters using supercritical carbon dioxideis studied, modelling a process with internal reflux generated by a thermal gradient at the top stage.A methodology for process design is proposed and applied to determine the relationships between thetemperature at the top stage (T1), the number of theoretical stages (N), and the solvent to feed ratio(S/F), with the aim of providing a quantitative comparison with the external reflux process. The internalreflux process is viable and, for stated process specifications (mass fraction and recovery of C20 + C22ethyl esters of 95%), provides comparable or better results than the external reflux process. For example,operating at 13.3 MPa and 50 ◦C, and keeping T1 in the range (66–70) ◦C, the specifications are attainedwith N and S/F in the range 16–30 and 88–120, respectively.©
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