In conclusion, the mcp gene from ISKNV cloned and highly
expressed in E. coli. This renatured recombinant MCP emulsified
with ISA 763 adjuvant at a dose of 50 mg/fish could induce better
humoral immunity and cellular immunity as well as protect
mandarin fish against ISKNV challenging. So the MCP may be
a candidate for vaccine development against infection by ISKNV in
mandarin fish.