against pathogens as oleuropein activated by β-glucosidase has very strong protein-denaturing, protein-crosslinking, and
lysine-alkylating activities (Konno et al., 1999). It has been described that the bactericidal effect of phenolic compounds is related to alterations in cellwall and cytoplasmic membrane which
could led to the disruption of the cell envelope.
Oleuropein promotes disruption of the peptidoglycan, which can
lead to cell death by destruction of the cell envelope. These changes
occur between 30 and 60 min of incubation in oleuropein supplied as
a pure compound in the growth medium (Rodríguez et al., 2009). The
fatty acid composition is altered in the presence of acidic phenols in
terms of what occurs in response to low temperature or high alcohol
concentration (Rozès and Peres, 1998).