In this study of all-cause mortality following ischemic stroke onset, living in an areawith more green space was associated with a lower mortality rate even after adjusting for demographic and clinical characteristics. Compared to living in the lowest quartile of green space, the hazard ratio for living in the second quartile was 0.90 (95% CI: 0.75, 1.08) and for living in the third quartile the hazard ratio was 0.78 (95% CI: 0.64, 0.95). The hazard ratiowas not lower for the 4th quartile (HR¼0.78, 95% CI: 0.63, 0.97). These findings were robust to further adjustment for residential proximity to a major roadway, and did not differ substantially across categories of a number of biological and socioeconomic factors. Continuous linear associations evaluated in secondary models did not achieve nominal statistical significance, although they suggested a lower mortality rate ratio with higher green space. There was no clear evidence of a nonlinear association, but we cannot rule out the possibility that power was not sufficient to detect nonlinearity.