Hen’s egg white lysozyme is used in winemaking to eliminate lactic acid bacteria and to control malolactic
fermentation. As eggs and derivatives are regarded as potential allergenic the European Commission
issued a directive that wine labels must include information about egg derived ingredients like lysozyme. As
a consequence the International Organisation for Wine and Vine (OIV) published a standard method for
measurement of lysozyme in wine by HPLC, which is based on a method developed at the University of
Bologna.