as well as cases that lacked biochemical confirmation; both of these approaches further reduce the risk of systematic under-reporting of incident diabetes. Further, although we believe most physicians and patients would regard myocardial infarction, stroke, and death to be more severe outcomes than new-onset diabetes (which in some cases was merely a biochemical change in glucose concentration from lower than 6·99 mmol/L [126 mg/dL] to higher than this threshold),