There is some evidence that chlorohydrin exposure in occupational settings is carcinogenic. Benson and Teta (1993) found significant increases in pancreatic, lymphopoietic and haematopoietic cancers in 278 workers assigned to ethylene and propylene chlorohydrin production units for a mean duration of 5.9 years, with a
mean follow-up of 36.5 years. A subsequent study (Olsen et al., 1997) found no significant increases in cancers in 1361 workers in a similar work setting, but
the duration of exposure in this latter study included people with just 30 days or more workplace experience.