It is customary that PS and PSD be considered as the main char- acteristics for printing toners. In addition, the effects of colorants on color toner production parameter have never been studied by the researchers. In this work, we first report on the significance of responding variables. As given in Table 1, the mixing time and agi- tation speed were chosen as the most influential parameters based on the literature. In the following, the most significant response outlined by the model will be thoroughly discussed and optimized