has demonstrated in normal, uninephrectomized,
and 75% nephrectomized rats that less
than 1% of an intravenous dose (8.9 mol Cd/kg) was
excreted by the end of the first week after exposure. Although
the cumulative urinary excretion of Cd was extremely
low in all three groups of rats, the 75% nephrectomized
rats excreted significantly more Cd than the
uninephrectomized or normal control rats during each day
of the 7-day study.