The differentiation of Th1, Th2 and Th17 cells is triggered
by IL-12 and interferon (IFN) γ, IL-2 and IL-4 and IL-6,
TGFβ, IL-21 and IL-23, respectively. Th1 responses are
characterised by the production of IL-2 and IFNγ, which
promote protective immunity against fungal infection through
activation of phagocytes, antigen presentation by antigen presenting
cells and production of opsonising antibodies
The differentiation of Th1, Th2 and Th17 cells is triggeredby IL-12 and interferon (IFN) γ, IL-2 and IL-4 and IL-6,TGFβ, IL-21 and IL-23, respectively. Th1 responses arecharacterised by the production of IL-2 and IFNγ, whichpromote protective immunity against fungal infection throughactivation of phagocytes, antigen presentation by antigen presentingcells and production of opsonising antibodies
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