Stroke is one of the leading causes of morbidity and mortality
worldwide with an estimated 5.7 million deaths and
≈50 million disability-adjusted life years lost every year.1
The introduction of intravenous thrombolysis with alteplase
for acute ischemic stroke has resulted in markedly improved
patient outcomes for those eligible to receive such treatment.2–4
Such treatment is safe and effective if administered within
4.5 hours and 64 hours postonset of symptoms (depending on
age), although this benefit is reduced, the later treatment is
given. Successful treatment therefore depends on early recognition
of symptoms, prompt arrival in hospital, and timely
computed tomography (CT) scanning.