SLN and NLC have shown many advantages for dermal delivery of drugs but unfortunately up to now there are no pharmaceutical products on the market containing lipid nanoparticles.
It could be shown already for various drugs that topical formulations containing lipid nanoparticles can enhance the penetration into the skin increasing treatment efficiency, target the epidermis, reduce systemic absorption and side effects.
Furthermore, an increased activity as well as prolonged activity was reported while the benefit/risk ratio was increased for many drugs.
Due to the superior performance of lipid nanoparticles containing topical formulations compared to market formulations, the market introduction of pharmaceutical topical formulations is expected in the near future.