To date, little is known about the use of alternative medicine in the treatment of bacterial vaginosis. One of the few reports on using natural remedies in treatment of this condition, a 2009 research review suggests that probiotics may be of some benefit to patients with bacterial vaginosis. Looking at 24 studies involving a total of 4,422 women, investigators found that taking supplements of the probiotic lactobacillus, alongside the antibiotic metronidazole, appeared to increase metronidazole's effectiveness.