Therapeutic doses of atropine sulfate for adults
range from 0.3 to 1 mg per os, 1 to 2 hours before the procedure.
The synthetic anticholinergic drug propantheline
bromide reportedly has fewer side effects than methantheline.
34 The usual adult dose of propantheline bromide for an
adult is 7.5 to 15 mg, taken orally 30 to 45 minutes before the
appointment. Because anticholinergics can cause undesirable
autonomic effects, especially through various drug interactions,
they should be used only in specific cases and only as a
last resort.