In most cases, the infection will go away without treatment in seven to 10 days. However, your doctor may recommend certain treatments to help ease symptoms until the disease has run its course. These can include:
prescription or over-the-counter topical ointments to soothe blisters and rashes
pain medication, such as acetaminophen or ibuprofen, to relieve headaches
medicated syrups or lozenges to ease painful sore throats
Certain at-home treatments can also provide relief from hand, foot, and mouth disease symptoms. You can try the following home remedies to help make blisters less bothersome:
Suck on ice or popsicles.
Eat ice cream or sherbet.
Drink cold beverages.
Avoid citrus fruits, fruit drinks, and soda.
Avoid spicy or salty foods.
Swishing warm salt water around in the mouth may also help relieve the pain associated with mouth blisters and throat sores. Do this several times a day or as often as needed.