The biochemical mechanisms underlying long-term regulation of
crustacean gill V-ATPase activity in response to salinity change are
only now being investigated. Recent studies show a substantial
increase or decrease in the abundance of mRNA for the V-ATPase B
subunit in the gill epithelia of some species in response to acclimation
to low or high salinities, suggesting alteration in transcription rates
and/or mRNA stability, leading to altered rates of enzyme synthesis.