The degeneration in the interstitial cells of
Leydig by the graded doses of calcium chloride may
have led to a reduction in serum testosterone concentrations
[40]. The low concentrations of serum testosterone
in cats treated with calcium chloride was further evidenced
by the qualitative study of testicular sections in
which significant fibrosis was seen with the medium and
highest doses. These have been due to a low concentration
of testosterone [41