However, there can be disadvantages to being a research participant. Study visits may take more time than what is typically required for an average patient, and will include the completion of a variety of questionnaires, as well as answering questions about depression symptoms. Moreover, research protocols frequently limit the dosing of the study medication, and often restrict the use of medications other than those being studied. In some double-blind studies, participants have the possibility of receiving placebo (sugar pill) instead of the active medication. Before enrolling in any study, potential participants will be told of the possibility and percent chance of being placed in the placebo group. Follow-up care may be provided for a limited time after participation in a placebo-controlled study. Most research appointments are scheduled Monday through Friday between the hours of 7:00 a.m. and 5:00 p.m. Within that time frame, we do try to be as flexible as possible to accommodate participants' schedules.