Essential oils are used in skincare products for perfuming and aromatherapy
purposes. In this study, the bioactivities of seven essential oils commonly
used and claimed for skincare namely citronella grass (Cymbopogon nardus L.),
lemongrass (Cymbopogon citratus DC), Kaffir lime (Citrus hystrix DC), holy
basil (Ocimum sanctum L.), sweet basil (Ocimum basilicum L.), plai (Zingiber cassumunar
Roxb) and ginger (Zingiber officinale Roscoe) were investigated. Investigation
of the in vitro susceptibility of the oils against Propionibacterium acnes (P.
acnes) using the broth microdilution technique revealed that citronella grass oil
exhibited the lowest minimum inhibitory concentration (MIC) and minimum bactericidal
concentration (MBC) at 0.005–0.3 and 0.6–1.2 ll/ml, respectively. The MIC
and MBC values of lemongrass oil were 0.6 ll/ml and those of kaffir lime oil and
holy basil oil were 5 ll/ml. Antioxidant activity using the DPPH free radical scavenging
assay showed that the IC50 values of holy basil oil (0.03 ll/ml), plai oil
(6.9 ll/ml) and citronella grass oil (2 ll/ml) were lower than that of ascorbic acid
(7.9 ll/ml). Anti-inflammatory activity of the oils determined using the 5-lipoxygenase
inhibition assay found that IC50 values of holy basil oil (0.04 ll/ml), kaffir
lime oil (0.05 ll/ml) and citronella grass oil (0.15 ll/ml) were less than that of
nordihydroquaretic acid (1.7 lg/ml). Since P. acnes has a role in the inflammation
of acne leading to scar formation, citronella grass oil may help to relieve acne
blemishes. However, further investigation in the form of clinical studies would
be necessary.
Essential oils are used in skincare products for perfuming and aromatherapy
purposes. In this study, the bioactivities of seven essential oils commonly
used and claimed for skincare namely citronella grass (Cymbopogon nardus L.),
lemongrass (Cymbopogon citratus DC), Kaffir lime (Citrus hystrix DC), holy
basil (Ocimum sanctum L.), sweet basil (Ocimum basilicum L.), plai (Zingiber cassumunar
Roxb) and ginger (Zingiber officinale Roscoe) were investigated. Investigation
of the in vitro susceptibility of the oils against Propionibacterium acnes (P.
acnes) using the broth microdilution technique revealed that citronella grass oil
exhibited the lowest minimum inhibitory concentration (MIC) and minimum bactericidal
concentration (MBC) at 0.005–0.3 and 0.6–1.2 ll/ml, respectively. The MIC
and MBC values of lemongrass oil were 0.6 ll/ml and those of kaffir lime oil and
holy basil oil were 5 ll/ml. Antioxidant activity using the DPPH free radical scavenging
assay showed that the IC50 values of holy basil oil (0.03 ll/ml), plai oil
(6.9 ll/ml) and citronella grass oil (2 ll/ml) were lower than that of ascorbic acid
(7.9 ll/ml). Anti-inflammatory activity of the oils determined using the 5-lipoxygenase
inhibition assay found that IC50 values of holy basil oil (0.04 ll/ml), kaffir
lime oil (0.05 ll/ml) and citronella grass oil (0.15 ll/ml) were less than that of
nordihydroquaretic acid (1.7 lg/ml). Since P. acnes has a role in the inflammation
of acne leading to scar formation, citronella grass oil may help to relieve acne
blemishes. However, further investigation in the form of clinical studies would
be necessary.
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น้ํามันหอมระเหยที่ใช้ในผลิตภัณฑ์ดูแลผิวสำหรับความสัมพันธ์ระหว่างบุคคลและวัตถุประสงค์อโรมา
ในการศึกษานี้ ฤทธิ์ทางชีวภาพของเจ็ดน้ำมันหอมระเหยโดยทั่วไป
ใช้และอ้างว่าเพื่อดูแลผิวคือตะไคร้หอม ( ตะไคร้ , ตะไคร้ nardus L )
( ตะไคร้ citratus DC ) , มะกรูด ( Citrus hystrix )
( กะเพราแดงกะเพราศักดิ์สิทธิ์ ( L . ) , โหระพาแมงลักโหระพา L . ) , ไพล ( ไพล
Roxb) and ginger (Zingiber officinale Roscoe) were investigated. Investigation
of the in vitro susceptibility of the oils against Propionibacterium acnes (P.
acnes) using the broth microdilution technique revealed that citronella grass oil
exhibited the lowest minimum inhibitory concentration (MIC) and minimum bactericidal
concentration (MBC) at 0.005–0.3 and 0.6–1.2 ll/ml, respectively. The MIC
and MBC values of lemongrass oil were 0.6 ll/ml and those of kaffir lime oil and
holy basil oil were 5 ll/ml. Antioxidant activity using the DPPH free radical scavenging
assay showed that the IC50 values of holy basil oil (0.03 ll/ml), plai oil
(6.9 ll/ml) and citronella grass oil (2 ll/ml) were lower than that of ascorbic acid
(7.9 ll/ml).กิจกรรมต้านการอักเสบของน้ำมันที่กำหนดโดยใช้ 5-lipoxygenase ยับยั้ง assay พบว่าค่า
ic50 ของน้ำมันโหระพา ( 0.04 จะ / ml ) , น้ำมันมะกรูด
( 0.05 จะ / มิลลิลิตร ) และน้ำมันตะไคร้หอม ( 0.15 จะต่อมิลลิลิตร ) มีค่าน้อยกว่าของ
nordihydroquaretic acid ( 1.7 LG / ml ) เนื่องจาก P . acnes มีบทบาทในการอักเสบของสิวรอยแผลเป็น
าการก่อตัวน้ำมันตะไคร้หอมอาจช่วยบรรเทารอยสิว
อย่างไรก็ตาม จากการศึกษาในรูปแบบของการศึกษาทางคลินิกจะ
จําเป็น
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