In the formalin test model, administration of the extract produced significant and dose dependent inhibition in both early (37.54%, and 50.18%) and late phases (45.5% and 67.24%) licking responses, at the tested doses of 250 and 500 mg/kg respectively (Table 3). Similarly, morphine exhibited noticeable inhibition of both the early phase (88.64%) and late phase (78.26%). In contrast, the treatment of animals with diclofenac sodium showed significant inhibition (76.81%) of the late phase, but not the early phase.
55