Duetoalargevarietyofsunscreens,itisimportanttostudyamongotherthings,theeffectofthevehicleonthe thicknessanduniformityofsunscreenfilms.Inthisstudy,wedeterminedthephysicalstabilityoffivesunscreensSPF15 (FAtoFG),containingornotPVP/eicosenecrosspolymer(PVP/EC),andtwodifferentself-emulsifyingbases(SEB), andalsoevaluatedtheinfluenceofthevehicleintheirSPF.Inthestudyofphysicalstability,formulationswerestored at25,37and45°C,for28days.Viscosityandrheologicalbehavioroftheformulationsweredeterminedusinga Brookfieldrheometer.InvestigationsoftheSPFwerecarriedoutinagroupof30volunteers(COLIPAmethodology). TheFCsamples(phosphate-basedSEB),withalowerthixotropy,showedstatisticallyhigherSPF(13.6)when comparedwithFB(non-ionicSEB),whichpresentedhigherthixotropyandaSPFof9.84.TheFEsample(phosphatePVP/EC)presentedthesameSPFastheFC,buthadahigherthixotropy.TheFBformulation(stablewith basedSEB/ higherthixotropy)showedthelowestSPFwhileFC(anunstableformulationwithlowerthixotropy)presentedahigher SPF.WeconcludedthatFEwasthebestformulationshowingahigherSPFandstabilityandthestudyofrheologycan helpthedevelopmentofsunscreens.
Duetoalargevarietyofsunscreens, itisimportanttostudyamongotherthings, theeffectofthevehicleonthe thicknessanduniformityofsunscreenfilmsInthisstudy, wedeterminedthephysicalstabilityoffivesunscreensSPF15 (FAtoFG),containingornotPVP/eicosenecrosspolymer(PVP/EC),andtwodifferentself-emulsifyingbases(SEB), andalsoevaluatedtheinfluenceofthevehicleintheirSPF.Inthestudyofphysicalstabilityat25 formulationswerestored, 37and45 ° C, for28daysViscosityandrheologicalbehavioroftheformulationsweredeterminedusinga Brookfieldrheometer.InvestigationsoftheSPFwerecarriedoutinagroupof30volunteers(COLIPAmethodology) TheFCsamples(phosphate-basedSEB), withalowerthixotropy, showedstatisticallyhigherSPF (13.6) เมื่อ comparedwithFB(non-ionicSEB), whichpresentedhigherthixotropyandaSPFof9.84TheFEsample(phosphatePVP/EC) presentedthesameSPFastheFC, buthadahigherthixotropyTheFBformulation (stablewith basedSEB/higherthixotropy) presentedahigher showedthelowestSPFwhileFC (anunstableformulationwithlowerthixotropy) SPFWeconcludedthatFEwasthebestformulationshowingahigherSPFandstabilityandthestudyofrheologycan helpthedevelopmentofsunscreens
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Duetoalargevarietyofsunscreens, itisimportanttostudyamongotherthings, theeffectofthevehicleonthe (FAtoFG) containingornotPVP / eicosenecrosspolymer (PVP / EC), andtwodifferentself-emulsifyingbases (SEB) at25, 37and45 ° C, for28days.Viscosityandrheologicalbehavioroftheformulationsweredeterminedusinga Brookfieldrheometer.InvestigationsoftheSPFwerecarriedoutinagroupof30volunteers (COLIPAmethodology) TheFCsamples (ฟอสเฟต basedSEB) withalowerthixotropy, showedstatisticallyhigherSPF (13.6) เมื่อ basedSEB / higherthixotropy) showedthelowestSPFwhileFC (anunstableformulationwithlowerthixotropy) presentedahigher SPF.WeconcludedthatFEwasthebestformulationshowingahigherSPFandstabilityandthestudyofrheologycan helpthedevelopmentofsunscreens
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duetoalargevarietyofsunscreens itisimportanttostudyamongotherthings theeffectofthevehicleonthe , , thicknessanduniformityofsunscreenfilms . inthisstudy wedeterminedthephysicalstabilityoffivesunscreensspf15 , ( fatofg ) containingornotpvp / eicosenecrosspolymer ( PVP / EC ) , andtwodifferentself emulsifyingbases ( SEB ) inthestudyofphysicalstability andalsoevaluatedtheinfluenceofthevehicleintheirspf , .formulationswerestored at25,37and45 ° C , for28days.viscosityandrheologicalbehavioroftheformulationsweredeterminedusinga brookfieldrheometer . investigationsofthespfwerecarriedoutinagroupof30volunteers ( colipamethodology ) thefcsamples ( ฟอสเฟต basedseb ) withalowerthixotropy showedstatisticallyhigherspf , ( 13.6 ) เมื่อ comparedwithfb ( ไม่ ionicseb ) whichpresentedhigherthixotropyandaspfof9.84 .thefesample ( phosphatepvp / EC ) presentedthesamespfasthefc buthadahigherthixotropy , . thefbformulation ( stablewith basedseb / higherthixotropy ) showedthelowestspfwhilefc ( anunstableformulationwithlowerthixotropy ) presentedahigher spf.weconcludedthatfewasthebestformulationshowingahigherspfandstabilityandthestudyofrheologycan helpthedevelopmentofsunscreens .
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