In the present study, we utilized the potential of protein fusion analysis
and recently developed computational software in order to identify
potential protein interactions and functional links in seven microalgal
species. SAFE is the only software currently available in the public domain
which has been developed specifically for the automated detection,
filtering and visualization of fusion events (Tsagrasoulis et al.,
2012). Most importantly, a performance comparison of the software
against a previous benchmark study of gene fusions showed that the results
by SAFE agree with other methods, while the software can also be
highly selective.