Global cognitive impairment was found in depressive patients in comparison to controls. Nevertheless, different profiles were demonstrated between groups. MDD and DD had greater impairment in attention (DD) and executive function (MDD) with a subcortical profile in memory (impairment in memory with good recognition ) while DdD had a cortical profile with more impairment in memory (impairment in memory with good recognition ) while DdD had a cortical profile with more impairment in memory (learning and recognition ) and language (BNT and SF). SSD showed a mixed profile, subcortical in memory buy with impairment in language (cortical), this group shows mild level of depression with moderate cognitive impairment. Therefore, SSD group could be considered in risk of dementia