A compromised nutrition has been associated with a poor prognosis in stable COPD patients with and without respiratory failure.27., 28. and 29. Nutritional status has been recently studied in 744 patients on long-term respiratory treatments (LTOT or LTMV);30 authors have found that fat-free mass (FFM), body mass index (BMI) below 20 and low serum albumin were the most sensitive parameters detecting malnutrition. Indeed, FFM appeared to be the most sensitive and relevant nutritional parameter according to patient's impairment and disability as assessed by FEV1 and 6-min walked distance.