Glatiramer acetate is generally well tolerated and unassociated with flulike symptoms. Immediate postinjection reactions associated with administration of glatiramer acetate in clude a local inflammatory reaction and an uncommon idiosyncratic reaction consision of flushing, chest tightness with palpitations,anxiety, or dyspnea, which resolves spontaneously without sequelae . Routine laboratory monitoring is not considered necessary in patients treated with glatiramer acetate ,and the development with the therapeutic efficacy of glatiramer acetate.