The case study presented in this article highlights the utility of early detection and intervention for children with KS. At 5 years old, Sarah was able to make large gains in self-soothing, emotion regulation, interpersonal relationships and coping mechanisms before her life was irreparably impacted. Additionally, Sarah's diagnosis precipitated the development of a treatment team to provide cohesive care for both Sarah and her family. While the diagnosis of KS in primary care practices will likely be rare, it is crucial that providers become aware of this diagnosis in order to make appropriate mental health and medical referrals, and provide the patient with the most comprehensive care. Further, understanding the multifaceted and pervasive nature of the developmental, psychological and family factors associated with this genetic disorder provides an illustration that underscores the need for primary care providers to comprehensively evaluate the impact that many genetically based problems may have on child development and family functioning, encouraging children and their parents to seek the assistance of a multidisciplinary team that includes mental health providers.