liquid drugs into a wet mist. As these devices aerosolize drug solution into a wet mist that floats deeply into the
patient’s airways as they inhale. In only a short duration, breathing the wet mist can relax patient’s bronchial
muscles and soothe raw air ways [16, 17]. These are small plastic devices into which the drug solution is placed and
are driven by a compressor (electric/battery operated) or a supply of compressed air or oxygen. A gas flow of about
6-8 litres/minute is normally required to drive the nebulizer [18]. Nebulizers use oxygen, compressed air or
ultrasonic power to break up medical solutions/suspensions into small aerosol droplets that can be directly inhaled
from mouth piece of the device. The aim of nebulizer therapy is to deliver a therapeutic dose of desired drug in the
form of an aerosol of respirable particles with in a fairly short period of time usually 5-15 min [19].Various
advantages of drug delivery directly to the airway include rapid onset of a therapeutic effect, reduced drug dose need
and limitation of systemic side effects, far outweigh those of any enteral or parentral route of administration [20].