To estimate the daily intake of arsenic from CHMs, the dose ingested should be taken into account. In accordance with the conservative principle, the maximum dose of each CHMs prescribed by the Chinese Pharmacopoeia was selected in the risk calculation (for example 9 g/d was selected as the dose in the risk calculation when 4.5e9 g/d was recommended for S. divaricata in Chinese Pharmacopoeia) (Chinese Pharmacopoeia Commission,2005). If the inorganic As concentration in CHMs is 200 ng/g (MCL) and consumption of 30 g CHMs by a 60 kg person daily, the proportion of the daily intake value to the ADI (126 mg) from FAO/WHO is 4.76%, which can be explained that a potential risk will exist if the proportion value of daily intake for inorganic As in CHMs is higher than 4.76%. So, the percentage of inorganic As in CHMs to ADI was calculated and shown in the Fig. 2. According to our data, daily contribution of inorganic arsenic in all samples from field to 218% using the same extract solution (1% HNO3) as that in this study. The former article indicated that it was difficult to explain the large differences in extraction efficiency and recovery among different samples. Zhao et al. (2010) gave the explanation for anomalously high recovery of 218% in white flour of wheat that total As concentration in this sample was very low at 21 ng/g, compared with 50e205 ng/g in other samples. Our results also
followed this explanation (Tables 2 and 3).
To estimate the daily intake of arsenic from CHMs, the dose ingested should be taken into account. In accordance with the conservative principle, the maximum dose of each CHMs prescribed by the Chinese Pharmacopoeia was selected in the risk calculation (for example 9 g/d was selected as the dose in the risk calculation when 4.5e9 g/d was recommended for S. divaricata in Chinese Pharmacopoeia) (Chinese Pharmacopoeia Commission,2005). If the inorganic As concentration in CHMs is 200 ng/g (MCL) and consumption of 30 g CHMs by a 60 kg person daily, the proportion of the daily intake value to the ADI (126 mg) from FAO/WHO is 4.76%, which can be explained that a potential risk will exist if the proportion value of daily intake for inorganic As in CHMs is higher than 4.76%. So, the percentage of inorganic As in CHMs to ADI was calculated and shown in the Fig. 2. According to our data, daily contribution of inorganic arsenic in all samples from field to 218% using the same extract solution (1% HNO3) as that in this study. The former article indicated that it was difficult to explain the large differences in extraction efficiency and recovery among different samples. Zhao et al. (2010) gave the explanation for anomalously high recovery of 218% in white flour of wheat that total As concentration in this sample was very low at 21 ng/g, compared with 50e205 ng/g in other samples. Our results also
followed this explanation (Tables 2 and 3).
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