ing inflammatory state over long periods of time, such as during
early lactation in dairy cows, might be associated with negative
consequences for the host. The review concludes that prolonged
systemic inflammation can cause significant changes in the energy
and lipid metabolism in different body tissues, lead to the development
of refractory states associated with immune suppression and
increased susceptibility to various diseases, and also artificially increase
host’s requirements in energy and nutrients, which during
the early lactation might exacerbate the catabolic state of the animal
and the negative energy balance.