The anti-microbial activity of various extracts of Oroxylum
indicum has been screened against fourteen pathogenic
bacteria (five gram-positive and nine gram-negative)
and seven pathogenic fungi by Kawsar et al. using disk
diffusion method. The crude ethyl acetate extract showed
mild to moderate activity against all bacteria and fungi
whereas the methanolic extract showed little activity
against bacteria but moderate activity against fungi.
The minimum inhibitory concentration of two isolated
flavonoid compounds from O. indicum were determined
against Bacillus subtilis, Staphylococcus aureus, Escherichia
coli and Shigella dysenteriae and the values were found to
be between 64–128μg/ml. A study by Thatoi et al. further
confirmed the activity by using different strains[36–37]
. Ali
et al. (1998) studied the effect of dichloromethane extract
of Oroxylum indicum against dermatophytes and wood
rot fungi and reported a strong antifungal activity in
dichloromethane extract of Oroxylum indicum[38]
.