It is best to travel with your own medication. Aspirin is common, Tylenol and Advil are not. Ask for an Ibuprofen (Advil active ingredient) as a pain reliever.
If there is an emergency dial 113 or 112. They are the Italian equivalent of USA's 911 and UK's 999.
If in distress yell AIUTO (pronounced ay-you-toe), which is Italian for HELP!
Serious crime is rare, however pickpockets and purse snatchers are common in large cities.