We hypothesized that DM patients, due to generalized neuropathy,
would present with coexisting sensorimotor, autonomic and central
neuropathy. Hence, the specific aims were to compare DM patients
with Healthy Volunteers (HV) in terms of 1) tactile detection and pain
to pinprick using von Frey monofilaments, 2) assessment of heart rate
variability, 3) CPM, and 4) the interaction between the different
parameters.