Results and DiscussionThe underlyin

Results and Discussion
The underlying concept of our experiments is illustrated schematically
in Fig. 1: when a virus particle binds to the antibody
receptor on a nanowire device, the conductance of that device
should change from the baseline value, and when the virus
unbinds, the conductance should return to the baseline value.
For a p-type nanowire, the conductance should decrease (increase)
when the surface charge of the virus is positive (negative)
(8). The conductance of a second nanowire device at which
binding does not occur during this same time period should show
no change and can serve as an internal control. Modification of
different nanowires within the array with receptors specific for
different viruses provides a means for simultaneous detection of
multiple viruses.