In clinical trials, an extract of C. asiatica in a 1% salve or 2% powder accelerated
healing of wounds (31). A formulation containing asiaticoside as the main
ingredient healed 64% of soiled wounds and chronic or recurrent atony that
was resistant to usual treatment (21). In an open clinical study, treatment of 20
patients with soiled wounds and chronic or recurrent atony with a galenical
formulation containing 89.5% C. asiatica healed 64% and produced improvement
in another 16% of the lesions studied (20). Local application of an extract
of the drug to second- and third-degree burns expedited healing, prevented the
shrinking and swelling caused by infection, and further inhibited hypertrophic
scar formation (11).