The current methodology for estimat

The current methodology for estimating sodium in the perspiration relies on collecting sweat via Macroducts sweat collection systems followed by lab-based analysis of the collected fluid
(Lee et al., 2010). However, such a protocol has several shortcomings for routine operation (Schazmann et al., 2010). These
include (i) a large sweat collection system that is uncomfortable to
wear thus hindering wearer's routine, (ii) bulky centralized
expensive instrumentation for sweat analysis that is incompatible
with on-body testing and (iii) compromised accuracy due to
evaporation of the sweat samples during their transport.
Such drawbacks can be addressed using wearable sensors.
Diamond's team demonstrated a wearable waistband sodium
sensor for on-body potentiometric monitoring of sodium
(Schazmann et al., 2010). Additional efforts aimed at on-body
monitoring of other electrolytes included measurements of sweat
chloride (Gonzalo-Ruiz et al., 2009), ammonium (Guinovart et al.,
2013a), potassium (Guinovart et al., 2013b) and pH (Bandodkar
et al., 2013a) in human perspiration using disposable strip, textilebased, and tattoo-like ISE, respectively. Parallel activity has been
devoted lately towards the development of portable wireless
transceivers for potentiometric sensors (Novell et al., 2013; Fay
et al., 2011). However these devices have not been applied for onbody electrolyte monitoring