Medication injection is the nursing skill and a part of the academic therapeutic nursing, which teaching in theory and practice in a laboratory nursing room and practice with the patients on the ward. The injection with patients, that may make causes of students stress, because students lack the skills to perform injection, forgotten steps of injection, incorrect injection technique and lack of knowledge of the injection. (Montha Limthongkul and Suphap Areeaua, 2009) Injection is an administration of drugs, that difficult. The injection technique is incorrect and lack of caution, which causes contamination, which makes the patient to infection. (Aumphol Sriraksa, 2011) Learning and teaching about the injection should be review, for an effectively injection administration and can practice nurses’ roles in administering injection without infection from the practice.