The antiadhesive property of cranberries probably helps to prevent UTI in 2 ways: first, it directly prevents E. coli from adhering to uroepithelial cells; and second, it selects for less adherent bacterial strains in the stool. A recent study showed that regular consumption of cranberry juice was also effective in cases in patients with UTI caused by antibiotic-resistant bacteria. Urine samples obtained from healthy volunteers who drank cranberry juice prevented uropathogenic E. coli isolates from adhering to isolated uroepithelial cells in bioassays. The antiadherent effect started within 2 h and persisted for up to 10 h after ingestion.