Avian coccidiosis is a parasitic di

Avian coccidiosis is a parasitic disease that has a substantial negative impact on the poultry industry (Yanet al., 2018). It is caused by Eimeria species that invade and damage intestinal epithelial cells, resulting in hemorrhagic inflammation, which ultimately leads to reduced weight gain and feed conversion, and the risk of contracting other diseases is increased due to the breakdown of the intestinal epithelial barrier Anticoccidial drugs and livevaccines are currently the primary methods for preventing and controlling chicken coccidiosis (Sun et al., 2014).Antimicrobial abuse in animal husbandry production has led to the development of drug-resistant strains aswell as residual concerns regarding the large influence of antimicrobial use on meat product safety and humanhealth (Liu et al., 2020). Furthermore, there are limitations to the live vaccine against Eimeria, such as thepotential detrimental impact on nutrient digestion rates during the peak circulation phase of the live oocyst vaccine