Use of systemic corticosteroids for at least 3 days.A single depo-injectable dose of corticosteroids is considered equivalent to a 3‑day course of systemic corticosteroids.For subjects receiving maintenance OCS, a temporary doubling of the maintenance dose for at least 3 days qualifies.An ED visit due to asthma that required systemic corticosteroids (as per above). An inpatient hospitalization due to asthma.