The size of a cell depends on intri

The size of a cell depends on intrinsic and extrinsic factors. For example, cell size can vary dramatically with cell type—some neurons or glia cells are up to 1,000 times larger than epithelial cells. Cell size is also influenced by the number of genome sets (ploidy). A haploid Drosophila epithelial cell is only about half the size of a diploid cell. A polyploid salivary gland cell, on the other hand, is more than 1,000 times larger than a diploid cell. Amongst the extrinsic factors, the availability of nutrients and temperature are well known for their effect on cell size. Starvation not only prolongs the cell doubling time in yeast and in Drosophila cells, it also reduces the size at which they divide.