oral manifestation of leukemia depe

oral manifestation of leukemia depend on the general status of patients. For instance before treatment leukemic infiltrates cause a wide range of oral disease. Typical oral manifestations of acute leukaemias include gingival swelling, oral ulceration, spontaneous gingival bleeding, petechiae, mucosal pallor, herpetic infections and
candidosis [4, 5, 6, 7, 13, 14]. Advanced cases may involve malaise, cervical lymphadenopathy, laryngeal pain and fever [8, 15]. Cervical lymphadenopathy, caused by infiltration of leukemic cells into the regional lymph nodes and hyperplasia of lymphatic issue particulary in Waldeyers ring. Enlarge tonsils and pharyngitis may be the initial complaint. Other uncommon orofacial signs of leukemia are pallor, parotid swelling and palatal pigmentation [16] . Radiographically leukemic infiltrates may produce destructive radiolucencies with loss of the lamina dura and erosion of the crestal alveolar bone