Methods:A prospective study was conducted in 18 children and 34 adults to assess the efficacy
and safety of nitazoxanide in the treatment of niclosamide- and praziquantel-resistant T.
saginatainfection. Nitazoxanide was administered twice daily for 3 days in 500-mg doses for
those aged over 14 years and at 20 mg/kg body weight/day in children aged 5—14 years. Posttreatment follow-up was undertaken at 1, 2, 4, 8, and 12 weeks for fecal samples for proglottides,
and to check the presence, number, and viability of Taenia eggs.