Poopó Lake (Spanish: Lago Poopó) is a large saline lake located in a shallow depression in the Altiplano Mountains in Bolivia at an altitude of approximately 3,700 metres. Because the lake is long and wide (90 km by 32 km) it makes up the eastern half of the Oruro Department, a mining region in southwest Bolivia.
The permanent part of the lake body covers approximately 1,000 km. The lake receives most of its water from the Desaguadero River which flows from Lake Titicaca at the north end of the Altiplano. Since the lake lacks any major outlet and has a mean depth of no more than 3 m, the surface area varies greatly.
The lake has been designated as a site for conservation under the Ramsar Convention .