Based on previous data extracted fr

Based on previous data extracted from the EOC administrative databases, a positive compositeoutcome variable was expected in approximately 30% of participants from the control group. Todetect a minimal clinically relevant difference (set at 6%) in that composite outcome variable between the intervention and the control groups with a 0.80 statistical power and a .05 significancelevel, a sample size of 1718 patients was estimated by Pearson χ2 test. Sample size calculation wasperformed using PASS statistical software version 15.0.3 (NCSS).