However, new vaccine formulations (HBV envelope-expressing DNA vaccine or peptide-based vaccines) that elicit HBVspecific CD8þT-cell responses in healthy volunteers or in CHB patients [28] were unable to achieve therapeutic effects in patients
However, new vaccineformulations (HBV envelope-expressing DNAvaccine or peptide-based vaccines) that elicit HBVspecificCD8þT-cell responses in healthy volunteersor in CHB patients [28] were unable to achievetherapeutic effects in patients