Alternatively, if dysregulated NMDA

Alternatively, if dysregulated NMDA-dependent synaptic plasticity, reflected
in an overabundance of weak synapses that are then pruned as a natural consequence of adolescent brain development, is the key driver, microglial activation would then represent a secondary signal (i.e., as in a clean-up operation), and strengthening of NMDA-related plasticity mechanisms would appear a more promising strategy