The use of organic modifiers such a

The use of organic modifiers such as metha-nol, ethanol and acetone, strongly affects the extraction efficiency.
Hydroorganic mixtures improved the recovery of HAAs from the
solid sample compared to the alkaline aqueous solution, as that
mixture had better solubilization properties, enhancing the release
of analyte from the solid sample matrix. After initial experiments,
it was found that the mixing solution containing sodium hydroxide
(1 mol L
1
), ethanol and acetone at a 70:10:20 ratio, respectively,
have the most efficiently separated and isolated HAAs from ham-burger patties. It is clear that the MAE technique, in comparison
with routine methods, reduces extraction time and helps rapidly
transfer the target analyte to the liquid phase.