3.4. Gastroprotective study
3.4.1. Pylorus ligation-induced gastric lesion
Gastric lesion measurements of pylorus-ligated rats showed that MEMC significantly decreased the ulcer area at the doses of 100, 250, and 500 mg/kg. Ranitidine (100 mg/kg), the standard drug used as the positive control in the study, also showed significant reduction of gastric lesion. The ulcer inhibition was found to be 77.6, 79.3, and 77.6%, respectively, while ranitidine showed 87.9% protection in comparison to the control group (Fig. 2).